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Drug Projects

Americans are bombarded with ads that begin with “Talk to your doctor about…” and plug in some pharmaceutical product. And many doctor-patient encounters end with a prescription of some sort. The rising cost of drugs is a major contributor to overall health costs in this country; whether or not we are getting value for money is an open question.

Moreover, a number of high-profile drugs have come under intense scrutiny in the last several years and Public Citizen has played an important role in many: Vioxx, Avandia, Viagra, Rezulin, Darvon, Meridia, Febuxostat, and Dsuvia.

Public Citizen has been assessing the quality and efficacy of drugs since its founding in 1971. When we feel that the information provided to doctors or patients is misleading, insufficient, or just plain wrong, we do not hesitate to express an opinion. Our book Worst Pills, Best Pills, our monthly print newsletter Worst Pills, Best Pills News, and our website WorstPills.org, have been at the forefront of the provision of information to patients. We also use the law, petitions, and letters to monitor the FDA and coax the agency into action. Our actions have contributed to more than two dozen drugs being pulled off the market. Public Citizen has also been instrumental in getting “black box” and other warnings in the product labeling of several dozen drugs.



acetaminophen (brand name: Tylenol)
Abbokinase (generic name: urokinase)
Accutane (generic name: isotretinoin)
Actos (generic name: pioglitazone)
Adalat (generic name: nifedipine)
Adasuve (generic name: loxapine)
aducanumab (brand name: Aduhelm)
Aduhelm (generic name: aducanumab)
albuterol (brand names: Proventil, Ventolin)
Aleve (generic name: naproxen)
Alli (generic name: orlistat)
alosetron (brand name: Lotronex)
Amitiza (generic name: lubiprostone)
amlodipine (brand name: Norvasc)
Amyvid (generic name: florbetapir F18 injection)
Anaprox (generic name: naproxen)
Androderm (brand name: transdermal testosterone patch)
apomorphine (brand name: Uprima, Apokyn)
Apokyn (generic name: apomorphine)
Apri-21 (generic name: desogestrel)
Arava (generic name: leflumide)
Arcalyst (generic name: rilonacept)
Arcapta Neohaler (generic name: indacaterol maleate)
Arcoxia (generic name: etoricoxib)
Aricept (generic name: donepezil)
Arymo (generic name: morphine sulphate, extended release)
atorvastatin (brand name: Lipitor)
Avandia (generic name: rosiglitazone)


baricitinib (brand name: Olumiant)
Baycol (generic name: cerivastatin)
bedaquiline (brand name: Sirturo)
Belsomra (generic name: suvorexant)
Benicar (generic name: olmesartan medoxomil)
bepridil (brand name: Vascor)
Bextra (generic name: valdecoxib)
Blood substitutes
Botox (generic name: botulinum toxin)
botulinum toxin (brand names: Botox, Myobloc)
bromfenac (brand name: Duract)
bromocriptine (brand names: Parlodel, Cycloset)
bupropion and naltrexone (Contrave)
butorphanol (brand name: Stadol)


Calan (generic name: verapamil)
canagliflozin (brand name: Invokana)
canakinumab (brand name: Ilaris)
Cardene (generic name: nicardipine)
Cardizem (generic name: diltiazem)
Cardura (generic name: doxazon)
Celebrex (generic name: celecoxib)
celecoxib (brand name: Celebrex)
cerivastatin (brand name: Baycol)
Chantix (generic name: varenicline)
Cialis (generic name: tadalafil)
cilostazol (brand name: Pletal)
Ciloxan (generic name: ciprofloxacin)
Cipro (generic name: ciprofloxacin)
ciprofloxacin (brand names: Ciloxan, Cipro)
cisapride (brand name: Propulsid)
Claritin (generic name: loratadine)
Contrave (bupropion and naltrexone)
Conzip (generic name: tramadol)
cough and cold medications
Covera (generic name: verapamil)
Crestor (generic name: rosuvastin)
Cyclessa (generic name: desogestrel)
Cycloset (generic name: bromocriptine)
Cylert (generic name: pemoline)


dapagliflozin (brand name: Farxiga)
Darvon (generic name: propoxyphene)
denosumab (brand name: Prolia)
Desogen (generic name: desogestrel)
desogestrel (brand names: Desogen, Mircette, Velivet, Apri-28, Kariva, Ortho-Cept, Reclipsen, Cyclessa)
Dexatrim (generic name: phenylpropanolamine)
dexfenfluramine (brand name: Redux)
Dilacor (generic name: diltiazem)
diltiazem (brand names: Cardizem, Dilacor, Tiazac)
dofetilide (brand name: Tikosyn)
donepezil (brand name: Aricept)
donislecel (purified allogeneic deceased donor pancreas derived Islets of Langerhans)
doxazosin (brand name: Cardura)
dronedarone (brand name: Multaq)
Dsuvia (generic name: sufentanil tablets)
Duract (generic name: bromfenac)
Dynacirc (generic name: isradipine)


Effient (generic name: prasugrel)
Elidel (generic name: pimecrolimus)
empagliflozin (brand name: Jardiance)
ertugliflozin (brand name: Steglatro)
esketamine (brand name: Spravato)
ethinyl estradiol/norelgestromin (brand name: Ortho-Evra)
etoricoxib (brand name: Arcoxia)
Exanta (generic name: ximelagatron)
Exelon (generic name: rivastigmine)
ezetimibe (brand name: Vytorin, Zetia)


Farxiga (generic name: dapagliflozin)
febuxostat (brand name: Uloric)
felodipine (brand name: Plendil)
fenfluramine (brand name: Pondimin)
fenfluramine and phentermine [fen-phen]
Flagyl (generic name: metronidazole)
florbetapir F18 injection (brand name: Amyvid)
fluvastatin (brand name: Lescol)
Forteo (generic name: teriparatide)


gadolinium-based contrast agents
gatifloxacin (brand name: Tequin)
gefitinib (brand name: Iressa)
gepirone (brand name: Travivo)
growth hormone


Halcion (generic name: triazolam)
hepatitis b vaccine
hepatitis e vaccine
Hespan (generic name: hydroxyethyl starch solution)
Hextend (generic name: hydroxyethyl starch solution)
Hormone replacement therapy
hydroxyethyl starch (HES) solution (brand names: Hespan, Hextend, Voluven)
hydroxyprogesterone caproate (brand name: Makena)


Ilaris (generic name: canakinumab)
indacaterol maleate (brand name: Arcapta Neohaler)
Invokana (generic name: canagliflozin)
Iressa (generic name: gefitinib)
Isoptin (generic name: verapamil)
isotretinion (brand name: Accutane)
isradipine (brand name: Dynacirc)


Jardiance (generic name: empagliflozin)


Kariva (generic name: desogestrel)


leflumide (brand name: Arava)
Lescol (generic name: fluvastatin)
Levitra (generic name: vardenafil)
Levo-T (generic name: levothyroxine sodium)
levothyroxine sodium (brand names: Levo-T, Levoxyl, Novothyrox, Synthroid, Thyro-tabs, Unithroid)
Levoxyl (generic name: levothyroxine sodium)
Lipitor (generic name: atorvastatin)
liraglutide (brand name: Victoza)
lofexidine (brand name: Lucemyra)
loratadine (brand name: Claritin)
lovastatin (brand name: Mevacor)
loxapine (brand name: Adasuve)
lubiprostone (brand name: Amitiza)
Lucemyra (generic name: lofexidine)


Makena (generic name: hydroxyprogesterone caproate)
meloxicam (brand name: Mobic)
Meridia (generic name: sibutramine)
Mestinon (generic name: pyridostigmine)
metronidazole (brand name: Flagyl)
Mevacor (generic name: lovastatin)
mibefradil (brand name: Posicor)
milnacipran (brand name: Savella)
mirabegron (brand name: Myrbetriq)
Mirapex (generic name: pramipexole)
Mircette (generic name: desogestrel)
Mobic (generic name: meloxicam)
montelukast (brand name: Singulair)
Morphine sulphate, extended release (brand name: Arymo)
Multaq (generic name: dronedarone)
muraglitazar (brand name: Pargluva)
Myobloc (generic name: botulinum toxin)
Myrbetriq (generic name: mirabegron)


naproxen (brand names: Aleve, Anaprox, Naprosyn)
nefazadone (brand name: Serzone)
Neupro (generic name: rotigotine)
nevirapine (brand name: Viramune)
nicardipine (brand name: Cardene)
nifedipine (brand names: Adalat, Procardia)
Nolvadex (generic name: tamoxifen)
Norvasc (generic name: amlodipine)
Novothyrox (generic name: levothyroxine sodium)
Nuplazid (generic name: pimavanserin)


olmesartan medoxomil (brand name: Benicar)
Olumiant (generic name: baricitinib)
orlistat (brand names: Alli, Xenical)
Ortho-cept (generic name: desogestrel)
Ortho-evra (generic name: ethinyl estradiol/norelgestromin)
oxycodone (brand name: OxyContin)
OxyContin (generic name: oxycodone)


parathyroid hormone
Pargluva (generic name: muraglitazar)
Parlodel (generic name: bromocriptine)
paroxetine (brand name: Paxil)
Paxil (generic name: paroxetine)
pemoline (brand name: Cylert)
Phenergan (generic name: promethazine)
phentermine and topiramate (brand name: Qnexa)
phenylpropanolamine (brand name: Dexatrim)
pimavanserin (brand name: Nuplazid)
pimecrolimus (brand name: Elidel)
pioglitazone (brand name: Actos)
Plendil (generic name: felodipine)
Pletal (generic name: cilostazol)
Polytrim (generic name: trimethoprim sulfate and polymyxin b sulfate)
Pondimin (generic name: fenfluramine)
Posicor (generic name: mibefradil)
pramipexole (brand name: Mirapex)
pramlinitide (brand name: Symlin)
prasugrel (brand name: Effient)
Pravachol (generic name: pravastatin)
pravastatin (brand name: Pravachol)
Procardia (generic name: nifedipine)
Prolia (generic name: denosumab)
promethazine (brand name: Phenergan)
propoxyphene (brand name: Darvon)
Propulsid (generic name: cisapride)
Protopic (generic name: tacrolimus)
Proventil (generic name: albuterol)
pyridostigmine (brand name: Mestinon)


Qnexa (generic name: phentermine and topiramate)
quetiapine fumarate (brand name: Seroquel)


Reclast (generic name: zoledronic acid)
Reclipsen (generic name: desogestrel)
Redux (generic name: dexfenfluramine)
Relenza (generic name: zanamivir)
remdesivir (brand name: Veklury)
Requip (generic name: ropinirole)
Rezulin (generic name: troglitazone)
rilonacept (brand name: Arcalyst)
rimonabant (brand name: Zimulti)
rivastigmine (brand name: Exelon)
rofecoxib (brand name: Vioxx)
ropinirole (brand name: Requip)
rotigotine (brand name: Neupro)
rosiglitazone (brand name: Avandia)
rosuvastin (brand name: Crestor)


salmeterol (brand name: Serevent)
Savella (generic name: milnacipran)
Seldane (generic name: terfenadine)
Serdolect (generic name: sertindole)
Serevent (generic name: salmeterol)
Seroquel (generic name: quetiapine fumarate)
sertindole (brand name: Serdolect)
Serzone (generic name: nefazadone)
sibutramine (brand name: Meridia)
sildenafil (brand name: Viagra)
simvastatin (brand name: Zocor)
Sirturo (generic name: bedaquiline)
Singulair (generic name: montelukast)
sotagliflozin (brand name: Zynquista)
Spiriva Respimat (generic name: tiotropium)
Spravato (generic name: esketamine)
Stadol (generic name: butorphanol)
Steglatro (generic name: ertugliflozin)
sufentanil tablets (brand name: Dsuvia)
surfactant (brand name: Surfaxin)
Surfaxin (generic name: surfactant)
Suvorexant (brand name: belsomra)
Symlin (generic name: pramlinitide)
Synthroid (generic name: levothyroxine sodium)


tacrolimus (brand name: Protopic)
tadalafil (brand name: Cialis)
tamoxifen (brand name: Nolvadex)
tegaserod (brand names: Zelmac, Zelnorm)
Tequin (generic name: gatifloxacin)
terfenadine (brand name: Seldane)
teriparatide (brand name: Forteo)
testosterone undecanoate (brand name: Tlando)
Thyro-tabs (generic name: levothyroxine sodium)
Tiazac (generic name: diltiazem)
tigecycline (brand name: Tygacil)
Tikosyn (generic name: dofetilide)
tiotropium (brand name: Spiriva Respimat)
Tlando (generic name: testosterone undecanoate)
Topamax (generic name: topiramate)
topiramate (brand name: Topamax)
tramadol (brand names: Conzip, Ultram)
transdermal testosterone patch (brand name: Androderm)
Travivo (generic name: gepirone)
triazolam (brand name: Halcion)
trimethoprim sulfate and polymyxin b sulfate (brand name: Polytrim)
troglitazone (brand name: Rezulin)
trovafloxacin (brand name: Trovan)
Trovan (generic name: trovafloxacin)
Tygacil (generic name: tigecycline)
Tylenol (generic name: acetaminophen)


Uloric (generic name: febuxostat)
Ultram (generic name: tramadol)
Unithroid (generic name: levothyroxine sodium)
Uprima (generic name: apomorphine)
urokinase (brand name: Abbokinase)


valacyclovir (brand name: Valtrex)
Valdecoxib (brand name: Bextra)
Valtrex (generic name: valacyclovir)
vardenafil (brand name: Levitra)
varenicline (brand name: Chantix)
Vascor (generic name: bepridil)
Veklury (generic name: remdesivir)
Velivet (generic name: desogestrel)
Ventolin (generic name: albuterol)
verapamil (brand names: Calan, Covera, Isoptin, Verelan)
Verelan (generic name: verapamil)
Viagra (generic name: sildenafil)
Victoza (generic name: liraglutide)
Vioxx (generic name: rofecoxib)
Viramune (generic name: nevirapine)
Voluven (generic name: hydroxyethyl starch solution)
Vytorin (generic name: ezetimibe)


Xenical (generic name: orlistat)
ximelagatron (brand name: Exanta)


zanamivir (brand name: Relenza)
Zelnorm (generic name: tegaserod)
Zetia (generic name: ezetimibe)
Zimulti (generic name: rimonabant)
Zocor (generic name: simvastatin)
zoledronic acid (brand names: Reclast, Zometa)
Zometa (generic name: zoledronic acid)
Zynquista (generic name: sotagliflozin)