1.0Public Citizenhttps://www.citizen.orgDiane Krauthamerhttps://www.citizen.org/author/dkrauthamer/rich600338<blockquote class="wp-embedded-content" data-secret="vWBsFo33t0"><a href="https://www.citizen.org/article/letter-on-ethical-concerns-with-the-alzheimers-disease-anti-inflammatory-prevention-trial-adapt-2/">Letter on Ethical Concerns with the Alzheimer’s Disease Anti-Inflammatory Prevention Trial (ADAPT)</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.citizen.org/article/letter-on-ethical-concerns-with-the-alzheimers-disease-anti-inflammatory-prevention-trial-adapt-2/embed/#?secret=vWBsFo33t0" width="600" height="338" title="“Letter on Ethical Concerns with the Alzheimer’s Disease Anti-Inflammatory Prevention Trial (ADAPT)” — Public Citizen" data-secret="vWBsFo33t0" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); /* ]]> */ </script> To subject healthy people to long-term NSAID use with all the potential adverse effects, without arranging to test the one drug thought most likely to be of benefit, seems highly unethical. It seems clear from available experimental data that some non-steroidal anti-inflammatory drugs (NSAIDs) are more likely to succeed than others and may be both safer and cheaper. Such a drug, logically, would be the one to test; this is why we supported the use of ibuprofen.https://www.citizen.org/wp-content/uploads/public_citizen_shared_link.jpg1200628