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More Information on the iCOMPARE and FIRST Trials

Follow-up Letter to OHRP Regarding the Unethical iCOMPARE Trial Comparing Standard and Long Work Schedules for Internal Medicine Residents

February 11, 2016

View as PDF.

View the iCOMPARE trial protocol.

View the University of Pennsylvania grant application to NIH.

Public Citizen and the American Medical Student Association again call on the Office for Human Research Protections (OHRP) to immediately suspend the iCOMPARE trial and to launch an investigation into the research. Documents recently obtained by Public Citizen from NIH provide additional clear evidence that the iCOMPARE trial, as designed and currently being conducted, violates basic ethical principles and federal regulatory requirements related to the protection of human subjects. OHRP’s failure to take action is troubling, and the agency’s continued inaction makes it a culpable party in this unethical research.

View OHRP’s March 28, 2016, interim response letter

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